From Lost in Translation to Paradise Found: Enabling Protein Biomarker Method Transfer by Mass Spectrometry

Update: 2014-10-07

Description

Translation of novel biomarkers into clinical care for the evaluation of therapeutic safety and efficacy has been slow and the degree of rigor with which new markers and methods to measure them are validated varies considerably. In an opinion article published in the July issue of Clinical Chemistry, Drs. Russell Grant and Andrew Hoofnagle provide some guidance with a minimal list of experiments that would allow potential users of novel biomarkers to evaluate their quality and potential reproducibility.

Comments

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From Lost in Translation to Paradise Found: Enabling Protein Biomarker Method Transfer by Mass Spectrometry

Hoofnagle, Andrew and Rodriguez, Henry

#box-pro-ellipsis-176096512113086{-webkit-line-clamp:2;}From Lost in Translation to Paradise Found: Enabling Protein Biomarker Method Transfer by Mass Spectrometry

From Lost in Translation to Paradise Found: Enabling Protein Biomarker Method Transfer by Mass Spectrometry

Hoofnagle, Andrew and Rodriguez, Henry

From Lost in Translation to Paradise Found: Enabling Protein Biomarker Method Transfer by Mass Spectrometry