Refinement of Variant Selection for the LDL Cholesterol Genetic Risk Score in the Diagnosis

Update: 2015-01-12

Description

Familial hypercholesterolemia is a genetic disorder characterized by increased plasma concentrations of low density lipoprotein cholesterol and premature symptoms of coronary heart disease. Early identification of at-risk individuals allows changes in lifestyle including dietary intervention and drug treatment. In the January 2015 issue of Clinical Chemistry, a Special Issue devoted to Molecular Diagnostics, a group of researchers in a multi-center study describes a genetic risk score procedure that distinguishes familial hypercholesterolemia patients from healthy subjects.

Comments

In Channel

Extreme PCR: Efficient and Specific DNA Amplification in 15-60 Seconds

2015-01-1218:22

Refinement of Variant Selection for the LDL Cholesterol Genetic Risk Score in the Diagnosis

2015-01-1209:29

Total and Cause Specific Mortality by Moderately and Markedly Increased Ferritin Concentrations

2015-01-0709:29

Critical Issues in International Biobanking

2014-12-2908:56

Integrative Bioinformatics Analysis Reveals New Prognostic Biomarkers of Clear Cell Renal Cell Carcinoma

2014-12-2308:56

Clinical Genomics: When Whole Genome Sequencing Is like a Wholebody CT Scan

2014-12-1514:34

December Audio Summary

2014-12-0108:26

Emory: Experience with Ebola Patients

2014-11-1308:43

Point/Counterpoint: The Quest for Clean Competition in Sports

2014-11-0408:43

Microfluidic Genotyping by Rapid Serial PCR and High-Speed Melting Analysis

2014-11-0408:43

November 2014 Audio Summary

2014-11-0407:05

Generation of a New Cystatin C–Based Estimating Equation for Glomerular Filtration Rate by Use of 7 Assays Standardized to the International Calibrator

2014-10-2808:57

Where Are All the New Omics-Based Tests?

2014-10-2107:55

Early Detection of Fragile X Syndrome: Applications of a Novel Approach for Improved Quantitative Methylation Analysis in Venous Blood and Newborn Blood Spots

2014-10-1320:45

From Lost in Translation to Paradise Found: Enabling Protein Biomarker Method Transfer by Mass Spectrometry

2014-10-0720:45

Three of 7 Hemoglobin A1c Point-of-Care Instruments Do Not Meet Generally Accepted Analytical Performance Criteria

2014-09-3012:58

Influence of the Confounding Factors Age and Sex on MicroRNA Profiles from Peripheral Blood

2014-09-2206:12

Podcasts Go Platinum!

2014-09-1607:04

Maternal Plasma RNA Sequencing for Genome-Wide Transcriptomic Profiling and Identification of Pregnancy-Associated Transcripts

2014-09-1608:38

September 2014 Audio Summary

2014-09-0406:55

00:00

Refinement of Variant Selection for the LDL Cholesterol Genetic Risk Score in the Diagnosis

#box-pro-ellipsis-176090598158416{-webkit-line-clamp:2;}Refinement of Variant Selection for the LDL Cholesterol Genetic Risk Score in the Diagnosis

Refinement of Variant Selection for the LDL Cholesterol Genetic Risk Score in the Diagnosis

Futema, Marta

Refinement of Variant Selection for the LDL Cholesterol Genetic Risk Score in the Diagnosis