Rimpoche continues the discussion of ignorance, the root of all delusions. The direct opponent to ignorance is wisdom. This wisdom is the wisdom of knowing the fundamental true nature of reality, which is “solving the mystery of life.” For achieving wisdom, Buddha presented the concept of non-existence. He did not mean we are not there. Rather, we exist relatively, which allows us to function, but in an absolute sense, we do not exist. So to achieve wisdom, we have to destroy our self-existing thoughts, because from there arises “I, Me, My” giving rise to all negativities. Rimpoche introduces the first two of six factors that contribute to the growth of delusions: base, and conditions. Our delusions grow from a karmic imprint, like a seed, which is the base. Secondly, the base, the imprint on our consciousness, only grows when it is connected with external causes and conditions.