Next in our series of Snackisodes on dangerous snacks is tremorgenic mycotoxicosis!

Specific mycotoxins discussed in today's episode include:

(1) Penitrem A, which is the most clinically significant tremorgenic mycotoxin in dogs and is produced by Penicillium crustosum

(2) Roquefortine C, which is primarily produced by Penicillium roqueforti; note that there is a harmless version of roquefortine C which is used in the production of roquefort cheese

(3) Verruculogen, which is associated with spoiled meats

References:

(1) Tremorgenic mycotoxicosis (canine). VINcyclopedia. Last updated by Galles, B on 10/10/23. www.vin.com

(2) Eriksen GS, Bernhoft A, Rundberget T, et al: Poisoning of dogs with tremorgenic Penicillium toxins. Med Mycol 2010 Vol 48 (1) pp. 188-96.

(3) Puschner B: Penitrem A and roquefortine. In: Plumlee KH (ed): Clinical Veterinary Toxicology Mosby, St. Louis, MO 2004 pp. 258-59

(4) Hayes AW, Presley DB, Neville JA: Acute toxicity of penitrem A in dogs. Toxicol Appl Pharmacol 1976 Vol 35 (2) pp. 311-20.