In this episode, Dr. William Davis delves into the fascinating world of L. Reuteri and its impact on skin health, gut and overall well-being. Learn about the potential benefits of this probiotic strain and its connection to gut health.

Topics Covered :

L. Reuteri and its Benefits:

• Loss in Modern Populations: Dr. William Davis highlights that Lactobacillus reuteri is largely absent in modern people due to antibiotic overuse, unlike in indigenous populations and wild mammals [ 01:16 ].
• Initial Benefits: Restoration of L. reuteri can lead to youthful musculature, increased oxytocin (enhancing love and affection), improved libido, and better social behavior [ 02:07 ].
• Skin Health:
  • L. reuteri dramatically increases dermal collagen, reducing wrinkles [ 02:31 ].
  • A clinical trial with 25 women showed a 15% increase in dermal layer thickness using L. reuteri with marine collagen peptides, hyaluronic acid, and astaxanthin [ 03:33 ].
  • Participants experienced more moisture and reduced wrinkle depth [ 05:19 ].
• Body Composition: The same trial unexpectedly showed significant waist circumference reduction, suggesting a targeting of abdominal fat and restoration of youthful muscle [ 05:31 ].
• Comparison to GLP-1 Agonists: Dr. Davis contrasts the benefits of L. reuteri with the drawbacks of drugs like Wegovy, which can lead to muscle loss and worsened health upon cessation [ 06:30 ].
• Strain Specifics: Dr. Davis mentions using a specific strain, L. reuteri LRDR, in his clinical trials, chosen for its effects in animals and humans [ 09:52 ].
• Dosage: Emerging evidence suggests that dosage matters, with higher doses potentially yielding better results [ 11:33 ].

Mechanisms of Action:

• Endotoxemia Reduction: L. reuteri helps reduce endotoxemia (bacterial breakdown products in the bloodstream), which is linked to various health issues like increased blood glucose, abdominal fat, and inflammation [ 13:39 ].
• Oxytocin and Cortisol: L. reuteri increases oxytocin, suppressing appetite, and reduces cortisol levels, which are linked to abdominal fat accumulation [ 16:54 ].

Other Beneficial Bacteria and Practices:

• Bacillus subtilis: Dr. Davis discusses using Bacillus subtilis to make sparkling juices, utilizing the DE111 strain for CO2 production [ 19:01 ].
• Saccharomyces boulardii: Recommended for minimizing gastrointestinal microbiome disruption when taking antibiotics [ 20:51 ].
• Lactobacillus crispatus: Crucial for female reproductive health, reducing miscarriage risk, premature delivery, and improving vaginal health [ 22:25 ]. It can be obtained through products like Gero Fem Dophilus Advanced or by making yogurt [ 24:38 ].

Prebiotics:

• Role: Prebiotics feed beneficial microbes, leading to the production of metabolites like butyric acid [ 27:38 ].
• Butyric Acid: Improves sleep, lowers blood pressure and sugar, reduces inflammation, and acidifies the skin, discouraging pathogens [ 28:19 ].
• Types: Inulin and fructooligosaccharides are widely metabolized, but other options include galactooligosaccharides, xylooligosaccharides, and polysaccharides [ 33:51 ].
• Hyaluronic acid: It is a fiber sourced from animals that blooms butyric acid producing species [ 34:35 ]

Wheat:

• Modern Wheat Issues: Dr. Davis reiterates the problems with modern high-yield semi-dwarf wheat, including glyphosate exposure [ 37:11 ].
• Differences in Wheat: The type of gliadin protein in wheat varies, affecting gastrointestinal tolerance [ 40:01