In this episode, we dive deep into the science of longevity with Courtney Van Bussum, COO of Longevity Launch Labs. Courtney shares her insights on the NAD (Nicotinamide Adenine Dinucleotide) pathway, a critical component in the aging process and how we can leverage it for longevity optimization. We explore the fascinating molecule 1-MNA (1-Methylnicotinamide), its unique role in the body, and how it helps lower levels of the NNMT (Nicotinamide N-methyltransferase) enzyme, which is associated with various age-related diseases and metabolic disorders.

Key Topics Discussed:

1. Introduction to the NAD Pathway:

   • Overview of the NAD pathway and its significance in cellular metabolism and aging.
   • The role of NAD+ in DNA repair, energy production, and maintaining cellular health.

2. Understanding 1-MNA (1-Methylnicotinamide):

   • What is 1-MNA, and what is it's role in the NAD story.
   • The unique properties of 1-MNA and its potential as a longevity molecule.

3. The NNMT Enzyme and Its Implications for Health:

   • Explanation of NNMT (Nicotinamide N-methyltransferase) and its impact on metabolic health and aging.
   • How elevated NNMT levels are linked to obesity, cancer, diabetes, and other age-related diseases.

4. How 1-MNA Lowers NNMT Levels:

   • The mechanism by which 1-MNA reduces NNMT activity, promoting healthier aging.
   • Potential benefits of 1-MNA in reducing inflammation, improving metabolism, and supporting overall health.
5.  How the immune system and NAD pathways are both key to longevity and health optimisation and how we can leverage and optimise both as we age. 

6. Longevity Optimization Strategies:

   • How targeting the NAD pathway and modulating NNMT activity can be part of a comprehensive longevity strategy.
   • Practical tips for integrating 1-MNA and other NAD-boosting supplements into your daily routine.

7. Courtney's Vision for the Future of Longevity Research:

   • Insights into the latest developments at Longevity Launch Labs.
   • The future of NAD research and its potential to revolutionize aging and healthcare.

Bio

Courtney Van Bussum is a dynamic entrepreneur and business leader who currently serves as the COO of Longevity Launch Labs, a pioneering incubator focused on advancing the Cellular and Longevity Medicine sectors. With a Bachelor of Science in Biomedical Engineering from Arizona State University, Barrett Honors College, Courtney has overseen several startups in the healthcare and medical arenas ranging from fitness applications to wearable medical devices. Her early career began as a strategy consultant in Scottsdale, Arizona where she honed her skills by working with Fortune 500 companies and startups, streamlining processes and driving innovation.

In 2020, Courtney joined the Boulder Longevity Institute, where she played a crucial role in enhancing the institute's core technology and operational systems. Two years later, she co-founded Longevity Launch Labs, where she has been instrumental in building the operational frameworks that have propelled the incubator to become a key connector in the industry. Under her leadership, Longevity Launch Labs offers a range of services including product co-formulation and development, distribution, product rollout strategy, and mentorship, all aimed at supporting companies and healthcare practitioners in the rapidly evolving field of longevity medicine. Through Launch's Longevity Impact Fund, Courtney also helps early-stage startups access key capital to further development of their healthcare innovations.

Having grown up around the world of medicine, Courtney understands that changing healthcare can only be achieved through creating innovative parallel systems that improve outcomes and experience. Her visionary leadership and deep expertise make her an invaluable voice in the conversation around healthcare innovation and longevity.

• Subscribe to our podcast for more expert insights on longevity, health optimization, and cutting-edge research.
• Visit Longevity Launch Labs' website for more information on 1-MNA and other groundbreaking research initiatives. 
• Connect with us on social media and share your thoughts on this episode using the hashtag #1-MNA

 

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