DiscoverMultiple Myeloma HubWhat might be the future applications for BCMA-directed bispecific antibodies in MM and other PCD?
What might be the future applications for BCMA-directed bispecific antibodies in MM and other PCD?

What might be the future applications for BCMA-directed bispecific antibodies in MM and other PCD?

Update: 2025-08-18
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The Multiple Myeloma Hub spoke with Sagar Lonial, Winship Cancer Institute of Emory University, Atlanta, US. We asked, What might be the future applications for B-cell maturation antigen (BCMA)-directed bispecific antibodies in multiple myeloma (MM) and other plasma cell dyscrasias?


In this interview, Sagar Lonial discussed the expanding role of BCMA-directed bispecific antibody therapies beyond relapsed/refractory MM, including their potential applications in high-risk smoldering MM and light-chain (AL) amyloidosis. Lonial also evaluated emerging strategies for optimizing dosing schedules, enhancing the patient experience, and mitigating treatment resistance.


This educational resource is independently supported by Johnson & Johnson. All content was developed by SES in collaboration with an expert steering committee. Funders were allowed no influence on the content of this resource. 


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What might be the future applications for BCMA-directed bispecific antibodies in MM and other PCD?

What might be the future applications for BCMA-directed bispecific antibodies in MM and other PCD?