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39: Learning Pain: Observational Effects on Placebo and Nocebo

39: Learning Pain: Observational Effects on Placebo and Nocebo

Update: 2025-09-14
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This episode dissects a systematic review and meta-analysis investigating observational learning (OL) as a mechanism for developing placebo hypoalgesia (pain relief) and nocebo hyperalgesia (pain exacerbation).


Meeuwis SH, Wasylewski MT, Bajcar EA, et al. Learning pain from others: a systematic review and meta-analysis of studies on placebo hypoalgesia and nocebo hyperalgesia induced by observational learning. Pain. 2023;164(11):2383-2396. doi:10.1097/j.pain.0000000000002943


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39: Learning Pain: Observational Effects on Placebo and Nocebo

39: Learning Pain: Observational Effects on Placebo and Nocebo

Anthony Novello