Age Reversal 2: NMN & NR, Metformin and Rapamycin -The Hype, The Choke and The Protector
Description
Another juicy installment in our age reversal series. Today we are talking about the science behind some of the most popular age reversal trends and trials. Here are some quick links to the studies mentioned in the video & for more information
The first human clinical study for NMN has started in Japan Kazuo Tsubota: https://www.nature.com/articles/npjamd201621
Metformin in aging and aging-related diseases: clinical applications and relevant mechanisms Sheng Chen:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8965502/
Effects of putative metformin targets on phenotypic age and leukocyte telomere length: a mendelian randomisation study using data from the UK Biobank Shan Luo, PhD :
https://www.thelancet.com/journals/lanhl/article/PIIS2666-7568(23)00085-5/fulltext
Rapamycin, the only drug that has been consistently demonstrated to increase mammalian longevity. An update, Author links open overlay panelZelton Dave Sharp:
https://www.sciencedirect.com/science/article/pii/S0531556523000876
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