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Summary 3.10 Fluoroquinolones

Chapter 3.10 discusses fluoroquinolones, a synthetic class of broad-spectrum antibacterial medications that inhibit bacterial DNA replication. Used to treat pneumonia, skin, and urinary tract infections, they are effective against gram-positive and gram-negative bacteria. Caution is needed due to the risk of serious side effects such as tendon rupture, neuropathy, and photosensitivity. Patients should avoid antacids and direct sunlight while taking this medication.

Multiple Choice Questions

1. Fluoroquinolones work by:
   a) Inhibiting protein synthesis
   b) Disrupting cell wall synthesis
   c) Blocking DNA replication
   d) Inhibiting RNA synthesis
2. Which of the following is a serious side effect of fluoroquinolones?
   a) Weight gain
   b) Tendon rupture
   c) Increased appetite
   d) Hair loss
3. Fluoroquinolones should be taken:
   a) With milk
   b) With antacids
   c) Two hours before or after meals
   d) With calcium supplements
4. Fluoroquinolones are contraindicated in children except for:
   a) Ear infections
   b) Common cold
   c) Complicated UTIs
   d) Allergies
5. Patients on fluoroquinolones should avoid:
   a) Sun exposure
   b) Drinking water
   c) Vegetables
   d) Carbohydrates

Answer Key

1. c) Blocking DNA replication
2. b) Tendon rupture
3. c) Two hours before or after meals
4. c) Complicated UTIs
5. a) Sun exposure