DiscoverThe BioDisruptors PodcastEp. 19 From Clarification to Sterilization: How Filters Safeguard Biopharma
Ep. 19 From Clarification to Sterilization: How Filters Safeguard Biopharma

Ep. 19 From Clarification to Sterilization: How Filters Safeguard Biopharma

Update: 2025-08-19
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In this episode, we explore how membrane filtration safeguards biopharma products such as antibodies, mRNA vaccines, and viral vectors. We walk through the key steps from microfiltration and ultrafiltration to virus and sterilizing filtration, showing how each stage protects purity and safety. We also examine the major challenge of fouling, where valuable molecules clog the very filters designed to protect them. Finally, we highlight strategies to overcome these obstacles, including prefiltration, advanced membrane materials, and smart process optimization. This episode offers a clear look into the science and innovation shaping the future of biopharma filtration.

Featured Article:  Membrane Technology for Sterilization and Virus Elimination of Biopharmaceuticals: Fouling Matters

(https://doi.org/10.1016/j.advmem.2025.100143)

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Ep. 19 From Clarification to Sterilization: How Filters Safeguard Biopharma

Ep. 19 From Clarification to Sterilization: How Filters Safeguard Biopharma

The BioDisruptors