Ep. 6 From Molecules to Medicine: The Complexities of Biologic Formulation
Update: 2025-05-06
Description
Formulating biologics is one of the most complex steps in drug development, requiring a deep understanding of molecular stability, delivery mechanisms, and regulatory constraints. This episode delves into the intricacies of excipient selection, aseptic manufacturing, and advanced delivery systems like lipid nanoparticles. We explore how formulation choices impact clinical performance and the future of personalized biologic therapies.
Featured Articles: Optimizing Excipient Properties to Prevent Aggregation inBiopharmaceutical Formulations (https://doi.org/10.1021/acs.jcim.3c01898)
Optimizing Your Biologic Drug Formulation Strategy (https://www.bioprocessonline.com/topic/optimizing-your-biologic-drug-formulation-strategy)
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