Ep. 20 Gene Therapy Vectors Compared: Viral vs Non-Viral
Description
In this episode, we explore the fascinating world of gene therapy vectors, the delivery systems that make genetic medicine possible. We look at how viral vectors such as lentiviruses, adenoviruses, and adeno-associated viruses each bring unique strengths, from powering CAR T cancer treatments to enabling cures for inherited blindness and spinal muscular atrophy. We also unpack the challenges, including risks of insertional mutagenesis, immune reactions, and cargo size limits that continue to drive scientific innovation. Finally, we turn to the fast growing field of non-viral vectors, including lipid nanoparticles and GalNAc conjugates, which are creating new opportunities for safer and more scalable therapies. Whether you are curious about the science or the future of medicine, this episode makes complex biotech breakthroughs easy to follow.
Featured Article: Viral and Non-Viral Vectors in Gene Therapy: Current State and Clinical Perspectives
United States
