Fecal Transplant May Help Reduce Infections in Long-Term Care Patients
Update: 2025-09-18
Description
- Fecal microbiota transplantation (FMT) is a therapy that restores balance in the gut by transferring healthy bacteria, helping patients escape the cycle of repeated antibiotic failures and infections
- A recent clinical trial found that FMT was safe and well tolerated in frail long-term care patients, showing fewer bloodstream infections and less antibiotic use than standard care
- Even though transplant recipients still carried resistant bacteria, they experienced fewer serious infections, proving that restoring microbiome diversity strengthens the body’s defenses against harmful microbes
- A national registry of 259 patients showed 90% were cured of recurrent Clostridioides difficile (C. difficile) infection after just one FMT treatment, with results lasting beyond six months
- FDA-approved products like Vowst and Rebyota now make FMT accessible in oral capsule and rectal forms, offering new hope for those facing stubborn gut infections
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