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In this comprehensive discussion, Hetal Karsan, Chair of Medical Education at United Digestive, explores how to manage complications of Primary Biliary Cholangitis (PBC) and their impact on patient quality of life. PBC is a chronic autoimmune cholestatic liver disease that primarily affects women—but is increasingly diagnosed in men. Dr. Karsan breaks down the progression from inflammation to fibrosis and cirrhosis, and emphasizes how early diagnosis and adherence to treatment with ursodeoxycholic acid (UDCA) can dramatically improve outcomes.

Learn practical strategies to monitor liver function, prevent and manage complications such as variceal hemorrhage, ascites, hepatic carcinoma, and osteoporosis. Discover the importance of normalizing alkaline phosphatase and bilirubin, supporting nutrition and vitamin levels, and reducing risk through lifestyle changes. Dr. Karsan also highlights how fatigue and pruritus impact daily life for patients with PBC and discusses both pharmacologic and non-pharmacologic ways to help. From screening recommendations to emotional support and patient education, this video is a vital guide for healthcare providers treating PBC.