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Discover the evolving landscape of Primary Biliary Cholangitis (PBC) treatment with Dr. Huiming Sooki Hon from United Digestive. In this expert-led discussion, Dr. Sooki Hon reviews both established and emerging therapies for PBC, beginning with first-line treatment using ursodeoxycholic acid (UDCA) and the importance of early diagnosis and biochemical monitoring. Learn why normalization—not just reduction—of alkaline phosphatase is becoming a new treatment goal, and why up to 40% of patients may require second-line therapy. Dr. Sooki Hon outlines the latest FDA-approved options, including obeticholic acid, elafibranor, and seladelpar, highlighting their mechanisms of action, efficacy, and key safety considerations. This video also explores promising investigational therapies and combination strategies aimed at slowing disease progression and improving symptom control. Whether you're a healthcare professional or a patient seeking updated information on PBC management, this comprehensive overview provides valuable insights into current standards and future directions.