DiscoverState of MedtechBCI: Paradromics Founder Matt Angle on BCI and the Race to High-Speed Brain Interfaces
BCI: Paradromics Founder Matt Angle on BCI and the Race to High-Speed Brain Interfaces

BCI: Paradromics Founder Matt Angle on BCI and the Race to High-Speed Brain Interfaces

Update: 2025-10-03
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Brain–computer interfaces are no longer science fiction. Matt Angle, Founder and CEO of Paradromics, joins Omar Khateeb to discuss how his company is building the world’s highest data–rate BCI.

From his neuroscience roots at Stanford to raising capital in Austin, Matt shares how Paradromics is preparing for first-in-human trials in ALS patients, why data rate is the real bottleneck, how their platform stacks up against Neuralink, and why investors like Saudi Arabia’s NEOM are betting on this future.

This episode covers the technology, the business, and the ethics behind connecting brains and machines.


Episode Breakdown:

00:00 – What is a Brain-Computer Interface (BCI)?

01:02 – Introducing Paradromics and CEO Matt Angle

02:01 – Matt’s background: neuroscience at Heidelberg & Stanford

03:25 – Early BCI research and limitations of older systems

04:46 – Why Paradromics moved to Austin, Texas

06:28 – How Paradromics technology works: recording at the neuron level

09:50 – Surgical process for BCI implantation

11:08 – Paradromics vs. Neuralink: 10x higher data rates

11:53 – First application: restoring speech for ALS & paralysis patients

13:43 – Potential of BCIs in mental health and mood tracking

15:30 – Psychiatry’s challenge: lack of data vs. future of “brain work”

19:06 – Strategic partnership with Saudi fund NEOM

21:27 – Paradromics’ 3–5 year roadmap: hardware + applications

24:10 – Why BCIs could disrupt pharmaceuticals and drug dosing

26:09 – M&A potential in BCI: role of Medtronic, Abbott, Boston Scientific

29:03 – Why medical devices have staying power vs. drugs

30:12 – Market size: $400B+ opportunity for BCIs

32:16 – Cybersecurity and neural data protection

33:49 – The FDA BCI Collaborative Community

34:42 – Upcoming BCI Society meeting in Banff, Canada

35:11 – Closing thoughts & where to find Paradromics online

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BCI: Paradromics Founder Matt Angle on BCI and the Race to High-Speed Brain Interfaces

BCI: Paradromics Founder Matt Angle on BCI and the Race to High-Speed Brain Interfaces

State of Medtech