Wound Care: Preventing Diabetic Amputations: Modulim CEO Amaan Mazhar on Imaging and Early Detection
Description
Every 20 seconds, someone in the world loses a limb to diabetes. Many of these amputations could be prevented with earlier detection.
In this episode, Amaan Mazhar, CEO of Modulim, explains how handheld imaging can spot circulation issues before ulcers form. We cover the science behind spatial frequency domain imaging, the economics of diabetic foot ulcers, and how proactive screening can save both lives and costs.
Episode Breakdown
00:00 – The epidemic of lower limb complications in the US
02:01 – Amaan Mazhar’s journey into medtech and imaging science
03:38 – From UC Irvine research to founding Modulim
04:52 – Diabetic foot ulcers and why they are so costly
05:27 – Traditional foot checks and why they often fail
07:02 – Modulim’s imaging: seeing below the skin surface
09:17 – Biomarkers that predict wounds before they form
10:52 – Case study: detecting an ulcer 13 weeks before it appeared
12:06 – Spatial frequency domain imaging explained
13:23 – Pivot from cart system to handheld device
15:54 – Reducing manufacturing costs and expanding access
17:18 – Identifying micro vs macrovascular issues
18:55 – Clinical traction with Kaiser Permanente and Fresenius
20:27 – Commercial model: hardware placement plus software subscription
22:01 – Expanding into military use for wound and burn assessment
25:03 – How the technology works: light patterns, multispectral imaging
27:21 – IP, UC Irvine partnership, and innovation pathway
28:10 – Regulatory strategy: 510(k) submission for handheld device
29:35 – Market opportunity: 30–40 million patients at risk
31:04 – Early detection as a data gap and how Modulim can close it
32:28 – Closing thoughts and call to action
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#Medtech #Diabetes #AmputationPrevention #Diagnostics #HealthcareInnovation #DigitalHealth