DiscoverBuilding Lifelong AthletesBLA 143: Do Statins Cause Dementia?
BLA 143: Do Statins Cause Dementia?

BLA 143: Do Statins Cause Dementia?

Update: 2025-08-19
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Description

Do life-saving statins secretly damage your brain? This episode tackles the controversial link between statins and dementia head-on. I'll explore the origins of the fear, from patient anecdotes to plausible science, and weigh it against the highest-quality evidence from large clinical trials. We'll separate the myths from the facts to reach a clear, evidence-based verdict on how these drugs truly affect your brain.


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CHAPTERS:


00:00 - Intro


01:07 - Where This Idea Came From


04:55 - The Possible Mechanism Cause of Symptoms


07:31 - The Scientific Evidence for Harm


11:20 - The Evidence Against The Claims


14:20 - Putting It All Together: A Unifying Framework


18:57 - Final Thoughts/ Guidance


23:32 - Outro


SELECTED REFERENCES:


https://pubmed.ncbi.nlm.nih.gov/12885101/


https://doi.org/10.4172/2329-6887.1000141


https://www.researchgate.net/publication/362574285_Mendelian_Randomization_Study_of_PCSK9_and_HMG-CoA_Reductase_Inhibition_and_Cognitive_Function


https://pmc.ncbi.nlm.nih.gov/articles/PMC5487843/


https://pmc.ncbi.nlm.nih.gov/articles/PMC5487843/


https://pmc.ncbi.nlm.nih.gov/articles/PMC5487843/


https://pmc.ncbi.nlm.nih.gov/articles/PMC5487843/


https://www.jacc.org/doi/10.1016/j.jacc.2021.04.075


Disclaimer This podcast is for entertainment, education, and informational purposes only. The topics discussed should not solely be used to diagnose, treat , or prevent any condition. The information presented here was created with an evidence based approach, but you please keep in mind that science is always changing and at the time of listening to this there may some new data that makes this information incomplete or inaccurate. Always seek the advice of your personal physician or qualified health care provider for questions regarding any medical condition.

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BLA 143: Do Statins Cause Dementia?

BLA 143: Do Statins Cause Dementia?

Jordan Rennicke, MD