Part 1. Adverse Events Following the Covid mRNA Vaccine. Are They Due to Multisystem Endothelial Dysfunction? What Role Does the Spike Protein Play?..And What are Some Potential Treatments?...
Description
Dr. Akos Koller, MD, PhD, DScProfessor EmeritusSemmelweis University, and Hungarian University of Sports ScienceBudapest, Hungary and New York Medical College, Valhalla NY, USA“Multisystem Endothelial Inflammation: A Key Driver of Adverse Events Following mRNA-Containing COVID-19 Vaccines. Vaccines 2025, 13, 855” PDF
Overview…Dr. Akos Koller, a specialist in microcirculation, discussed the adverse effects of mRNA COVID-19 vaccines, particularly endothelial inflammation caused by the spike protein. He noted that a healthy microcirculation is crucial for recovery from COVID-19 and vaccines. The spike protein from mRNA vaccines is more pathogenic than the natural Covid virus, as it persists longer and can degrade the endothelial glycocalyx, leading to inflammation and vascular injury. Dr. Koller suggested that exercise and products that help restore the glycocalyx might be beneficial in those with post vaccine syndrome (PVS). He also highlighted the individual variability in vaccine responses and the need for personalized medical guidance regarding vaccination and vaccine types.
Things To Be Explored…
* Supplements that can help restore glycocalyx, which protect the endothelium from circulating inflammatory cell and thrombus formations and also serve as a permeability barrier.
* Conduct biochemical, in vitro and in vivo experiments to see how the spike protein produced by the mRNA vaccines can be broken down.
* Encourage exercise and physical activity as a potential intervention for post-vaccination and long COVID syndromes.
* Discuss the potential use of blood thinners (anticoagulants) as an adjuvant treatment for post-vaccination syndrome.
* Bring together expert panels from various medical societies to review the benefits and risks of COVID-19 vaccines and provide updated, patient-specific (age, gender, race, health conditions, etc.) guidelines.
Dr. Akos Koller’s Background…Dr. Akos Koller, MD, PhD, is an emeritus professor at Semmelweis University, and Hungarian University of Sports Science, Budapest, Hungary and New York Medical College, Valhalla NY, USA.
Dr. Koller’s background is in microcirculation and his interest in the topic of multi-system endothelial inflammation following mRNA COVID-19 vaccines are highlighted. Dr. Koller explains his background in microcirculation, focusing on very small vessels, such as arterioles, capillaries venules and lymphatics, that support all organs and tissues.
Importance of a Healthy Microcirculation…He emphasizes the importance of healthy microcirculation in dealing with inflammatory diseases and viruses like COVID-19. Dr. Koller notes that people with pre-existing conditions like diabetes or hypertension were more affected by COVID-19 and post-COVID syndrome. He stresses that healthy microcirculation, especially the endothelium, as a first line of defense is crucial for recovering from diseases and reducing post-vaccination syndrome.
Mechanisms of Inflammation from COVID-19 and mRNA Vaccines…Kirk Hamilton PA asks about the causes of inflammation from COVID-19 and mRNA vaccines, specifically the role of the spike protein. Dr. Koller explains that mRNA technology involves a liposome membrane package and mRNA that produces the spike protein inside parenchymal (endothelium, skeletal muscle, cardiac muscle, and neural cells etc.) cells. He notes that the mRNA in vaccines is modified to resist enzymatic breakdown, leading to prolonged production of the spike protein. Dr. Koller mentions that individual responses to the vaccine vary, maybe because some people are able to breakdown the mRNA and spike protein faster than others. That is what we should learn.
Comparison of Spike Proteins from Natural Infection and Vaccines…Kirk Hamilton questions the differences between the spike protein from the natural COVID-19 virus and the one produced by mRNA vaccines. Dr. Koller states that the spike protein from mRNA vaccines is more pathogenic and can spread throughout the body.
He explains that coronaviruses have been present for decades, but the COVID-19 virus from Wuhan was different and caused a “panic” response. Dr. Koller notes that the second or third doses of the vaccine can lead to more adverse effects, and guidelines have been updated to restrict vaccination to certain groups.
Challenges with mRNA Vaccines and Alternative Vaccines…Kirk Hamilton expresses confusion over why the spike protein, a toxic agent, is used in vaccines. Dr. Koller explains that mRNA vaccines were chosen for their ability to elicit a strong immune response, but they can also cause side effects. He mentions that other vaccines, like the Sinovac’s CoronaVac (COVID-19 vaccine) that used an inactivated virus was made in China do not elicit as strong an immune response but may have fewer side effects. He also mentions the Russian Sputnik, Gam-COVID-Vac (Viral vector vaccines vs. mRNA vaccines: The differences ) and this may deliver less spike protein to the cell. He notes not hearing about significant side effects (spike protein-induced) from these two vaccines.Dr. Koller suggests that the choice of vaccine should be individualized based on the person’s health status and response to the vaccine.
Mechanisms of Endothelial Inflammation and Importance of the Glycocalyx…Kirk Hamilton asks how the spike protein causes endothelial inflammation and whether it is worse from the infection or the vaccine. Dr. Koller explains that the spike protein can degrade the glycocalyx, a fine structure on the endothelium that prevents cells from “sticking.” He notes that the glycocalyx is important for maintaining healthy endothelial function and preventing inflammation. Dr. Koller suggests that restoring the glycocalyx could provide a defense against the spike protein.
Potential Treatments and Preventive Measures…Kirk Hamilton mentions products that enhance the glycocalyx, such as those made from seaweed. (Arterosil is made primarily from rhamnan sulfate, a specialized sulfated polysaccharide extracted from the rare green seaweed, Monostroma nitidum). It also contains a blend of fruit and vegetable extracts rich in antioxidants.
Kirk Hamilton mentions the potential use of enzymes like nattokinase to break down the spike protein and improve endothelial health. Dr. Koller shares that experiments have shown that restoring the glycocalyx with similar molecules can reduce permeability and edema. Dr. Koller emphasizes the importance of individualized treatment and the need for further research on effective interventions.
Personal Experiences and Recommendations…Kirk Hamilton asks Dr. Koller if he plans to get more mRNA vaccines and whether he encourages his family to get vaccinated. Dr. Koller states that he has not experienced severe illnesses and does not plan to get more vaccines. He mentions that his family members have had different experiences with the vaccine, highlighting the individual variability in response.
Final Thoughts and Closing Remarks…Dr. Koller recommends exercise and a healthy lifestyle to maintain vascular health and reduce the risk of adverse reactions to vaccines. Dr. Koller stresses the importance of expert consensus in making medical decisions and updating guidelines based on new data. He suggests that the benefits and risks of interventions should be carefully considered and individualized.
Kirk Hamilton asks Dr. Koller who he would recommend getting the COVID vaccine, and Dr. Koller emphasizes the need for expert consultation and individualized decisions. The conversation concludes with Dr. Koller expressing hope for continued collaboration and open discussion in medical research.
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Highlights…
COVID 19 VIRUS CREATION HISTORY; PATHOGENICITY OF THE SPIKE PROTEIN CREATED BY THE NATURAL INFECTION VERSUS BY THE mRNA VACCINE; AND TREATMENTS FOR SPIKE PROTEIN DETOXIFICATION - PODCAST INTERVIEW with Peter McCullough, MD. Start at 4:00-58 min:sec. Excellent explanation and historical timeline with practical recommendations for the health professionals and lay public on diagnosis and treatment of “spike protein” illness whether from the natural infection or mRNA Covid 19 vaccine. A “Must Listen.”
NUCLEAR WAR - “Playing Nuclear Roulette”. Tucker Carlson interviews nuclear expert Ivana Hughes from Columbia University.
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