Dr. János Szebeni, MD, PhD, DSc, Med. Habil.Nanomedicine Research and Education CenterInstitute of Translational Medicine Semmelweis University1089 Budapest, Hungary“Multisystem Endothelial Inflammation: A Key Driver of Adverse Events Following mRNA-Containing COVID-19 Vaccines. Vaccines 2025, 13, 855” Interview Overview…Dr. Janos Szebeni, MD, PhD specialties are in nanotechnology and immunology. He is the Director of the Nano Medicine Research and Education Center at Semmelweis University in Budapest, Hungary. In his co-authored article “Multisystem Endothelial Inflammation: A Key Driver of Adverse Events Following mRNA-Containing COVID-19 Vaccines. Vaccines 2025, 13, 855” he discusses the adverse events following COVID-19 mRNA vaccines, particularly in the context of multi-system endothelial inflammation. He highlighted the role of the spike protein in causing inflammation and autoimmunity, noting that the lipid nanoparticles used for vaccine delivery are more prone to adverse effects than traditional vaccines. Dr. Szebeni emphasized the potential risks of the spike protein, including its toxicity and propensity to bind to cell membranes, which can lead to autoimmunity and autoimmune disorders. He also expressed concerns about the vaccine’s impact on cancer risk and DNA integrity.

Dr. Szebeni’s Background and Interest in Endothelial Inflammation… Dr. Szebeni provides an overview of his educational background, including his MD, PhD in nanotechnology and immunology, and his current position at Semmelweis University. He explains his interest in endothelial inflammation and post-vaccine syndrome, noting his extensive experience in drug delivery and liposome research. Dr. Szebeni describes post-vaccine syndrome as a set of acute or long-lasting symptoms occurring after COVID vaccines, mainly inflammatory and can be autoimmune in nature. He mentions that some of the problems with the vaccines were familiar to him due to his experience with other liposomes and lipid nanoparticle products.

Mechanism and Goal of Lipid Nanoparticles…Dr. Szebeni explains the goal of packaging mRNA material in lipid nanoparticles is for more efficient immunity against the Covid virus. He highlighted the urgency of developing a vaccine against COVID at the beginning of the pandemic and the success of mRNA technology for other conditions.

The discussion touches on the adverse events associated with the vaccines, with Dr. Szebeni noting that he has identified eight inherent structural and functional features of the two mRNA vaccine formulations applied for people that can be linked to adverse effects.

Thus, the formation of the spike protein on ribosomes is not the only a contributing factor to the problem.

Spike Protein and Autoimmunity…Dr. Szebeni discusses the toxicity of the spike protein and its role in triggering autoimmunity and causing inflammation. He explains that the spike protein is synthesized in the cytoplasm and can be secreted to the blood, expressed on the cell surface, or processed and presented in immune cells.

Dr. Szebeni mentions the debate over whether the mRNA COVID vaccination increases the risk of cancer, noting the possible presence of oncogenic DNA segments in some vaccine lots.

Duration of Spike Protein and Treatment Options…Dr. Szebeni explains that the spike protein should be present only in certain immune cells called antigen presenting cells but is found in the blood and body cells due to a deviation from the natural immunogenicity process.

Conclusion and Personal Opinion…Dr. Szebeni emphasizes the need for a better understanding of the mechanism behind the vaccine’s adverse effects and the importance of developing the mRNA technology in a safer manner.

The discussion concludes with Dr. Szebeni expressing his willingness to share ideas on making the technology safer but noting that it would require more detailed interviews.

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Highlights…

COVID 19 VIRUS CREATION HISTORY; PATHOGENICITY OF THE SPIKE PROTEIN BY THE NATURAL INFECTION VERSUS BY THE mRNA VACCINE; TREATMENTS FOR SPIKE PROTEIN DETOXIFICATION - PODCAST INTERVIEW with Peter McCullough, MD. Start at 4:00-58:00 min:sec. Excellent explanation and historical timeline of the origins of the Covid 19 virus; lack of pathogenicity of the spike protein from the pre-pandemic Corona viruses; comparison to the significant and increasing pathogenicity of the altered spike proteins from the natural Covid 19 infection and mRNA vaccines with practical recommendations for health professionals and lay public on the diagnosis and treatment of “spike protein” illness whether from the natural infection or the mRNA Covid 19 vaccine. A “Must Listen.” This interview complements the information in Part 1 and Part 2 of “Adverse Events Following the Covid mRNA Vaccine. Are They Due to Multisystem Endothelial Dysfunction? What Role Does the Spike Protein Play? and What are Some Potential Treatments?...”

ORGAN TRANSPLANTATION - ETHICS - FORCED ORGAN TRANSPLANTS - The Truth about Organ Donation with Jan Jekielek. Dr. Varon and Jan Jekielek expose disturbing truths about organ procurement—from China’s forced harvesting to ethical violations in U.S. hospitals. Joe Veron, MD, Independent Medical Alliance, Oct 17, 2025

Nutrition, Prevention and Integrative Medicine…

CHILDHOOD VACCINES - DNA FRAGMENTS - Childhood Vaccines Contain Trillions of Human Fetal DNA Fragments Capable of Genomic Integration. Peer-reviewed study found human DNA fragments in fetal cell–derived vaccines exceeding the FDA limit by up to 2,760% and mapped their potential integration sites to genes associated with autism. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Oct 20, 2025.1) Epidemiologic and Molecular Relationship Between Vaccine Manufacture and Autism Spectrum Disorder Prevalence. “…Vaccines manufactured in human fetal cell lines contain unacceptably high levels of fetal DNA fragment contaminants. The human genome naturally contains regions that are susceptible to double strand break formation and DNA insertional mutagenesis…”

CHILDHOOD VACCINES - ALUMINUM - Five Studies Link Aluminum Vaccine Adjuvants to Asthma, Autism, and SIDS. Mass aluminum-based hyper-vaccination of children is pouring kerosene on the fire of chronic disease. Nicolas Hulscher, MPH, Focal Points (Courageous Discourse), Jun 19, 2025.1) Association Between Aluminum Exposure From Vaccines Before Age 24 Months and Persistent Asthma at Age 24 to 59 Months. “…In a large observational study, a positive association was found between vaccine-related aluminum exposure and persistent asthma…”2) Reviewing the association between aluminum adjuvants in the vaccines and autism spectrum disorder. “…The association between aluminum adjuvants in the vaccines and autism spectrum disorder is suggested by multiple lines of evidence…”3) Do aluminum vaccine adjuvants contribute to the rising prevalence of autism? “…The application of the Hill’s criteria to these data indicates that the correlation between Al in vaccines and ASD may be causal. Because children represent a fraction of the population most at risk for complications following exposure to Al, a more rigorous evaluation of Al adjuvant safety seems warranted…”4) Aluminum in brain tissue in autism.”…We have made the first measurements of aluminum in brain tissue in ASD and we have shown that the brain aluminum content is extraordinarily high. We have identified aluminum in brain tissue as both extracellular and intracellular with the latter involving both neurons and non-neuronal cells. The presence of aluminum in inflammatory cells in the meninges, vasculature, grey and white matter is a standout observation and could implicate aluminum in the etiology of ASD…”5) The Immature Infant Liver: Cytochrome P450 Enzymes and their Relevance to Vaccine Safety and SIDS Research. “…The CYP450 system plays a critical role in metabolic detoxification, including substances such as aluminum salts, which are widely used as vaccine adjuvants…”

EYE INJURY - PICKLEBALL - <a href="https://www.thefocalpoints.com/p/pickleball-injuries-spike-