In this episode of The State of MedTech, Omar M. Khateeb is joined by Carolina Aguilar, CEO and Co-Founder of In Brain NeuroElectrics, a company pioneering breakthroughs in brain-computer interfaces (BCI) and graphene-based neural technology.

In this fascinating discussion, Carolina delves into the revolutionary potential of graphene in brain health, its biocompatibility, and its ability to decode and modulate the brain at micro-precision. Discover how this BCI therapeutic approach could transform treatments for Parkinson's disease, epilepsy, and other neurological conditions.

Episode Breakdown:

00:00 - Introduction: AI, Patient Care, and the Future of MedTech

00:47 - Welcoming Carolina Aguilar, CEO of InBrain Neural Electrics

01:04 - The Innovation Behind In Brain: Leveraging Graphene

01:58 - Carolina's Background: From Pharmacy to Virginia Tech Neuroscience

03:07 - The Career Pivot: Cosmetics, Medtronic, and Deep Brain Stimulation (DBS)

03:53 - Insights on Parkinson's and Pesticides

05:45 - The Founding Story of In Brain: Transition from Medtronic

07:05 - The Need for Transformative Tech: Why DBS is Only 60-80% Effective

08:15 - Why Graphene? Solving the Resolution & Control Problem

09:25 - Graphene's Unique Properties: Strength, Precision, and Stability

10:36 - Decoding (Reading) vs. Modulating (Writing) the Brain

11:32 - Precision Matters: Limitations of Current DBS Metals

12:59 - Graphene as a Platform Material for the Nervous System

14:23 - Introducing BCI Therapeutics: A New Category

15:48 - BCI Therapeutics vs. DBS: Targeting Gait, Speech & Fine Movement

17:46 - In Brain's Device Explained: The Intelligent Neural Controller

18:22 - Closed-Loop System: The "Mini Neurologist in Your Brain"

20:29 - Why 1024 Contacts are Possible with Graphene

21:47 - Minimally Invasive Surgery & Reducing Complications

23:14 - Leveraging AI: The Clinical Co-Pilot App (Patient Empowerment)

24:38 - Addressing Unsolved Parkinson's Symptoms: Gait and Speech

25:47 - World's First Human Graphene-Based BCI Procedure

26:10 - The Graphene Flagship & De-risking Biomedical Applications

27:38 - The Future Standard: Why AI & Compute Demand Graphene

28:51 - Graphene & Semiconductors: Scalability vs. Manual Assembly of Metals

31:07 - Why Patients are the Best Doctors for Themselves

33:51 - Commercialization & Next Steps: Clinical Trials and Funding

35:05 - Strategic Choice of Parkinson's for Proof of Superiority

35:50 - Upcoming Conferences for Clinicians and Investors

37:39 - Closing Remarks & Where to Follow InBrain Neural Electrics

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